I have had limited experience with video games, but I'm a sucker for first person shooters.
I love the Call of Duty's that I've played, but Modern Warfare 3 and Black
Op's (zombies mode only) are my favorites.
The Halo games are amazing and I can't wait for Halo 4 and the return of the Master Chief. My overall favorite Halo is Halo: Reach.
I loved Battlefield: Bad Company 2, but I love Battlefield 3 more. (I am by no means a CoD fanboy)
The Assassin's Creed series is amazing and I can't pick a favorite one.
Let's not forget Batman: Arkham Asylum and Batman: Arkham City.
The Elder Scrolls V: Skyrim is my favorite RPG ever with Fallout: New Vegas a close second.