What's up? - My top favourite, HOW do you answer that? Does it mean how are you or what have you been up to or...what?
How are you? - Well, I don't look alright, but I'll say I am anyway because it's easier than the real answer, and you're probably not that bothered anyway.
Whats wrong? - Quite a lot of things, but I can't identify them/don't want to talk about it.
What do you think it is/What do you want to do? - When asked by doctors, erm, isn't it their job to tell me what it is and what to do about it?
Aww, how come you didn't come out? - Erm, probably because I wasn't invited.
There's probably quite a few more, but I can't think of them at the moment.