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I would think that you would be safe going. They usually say not to travel by plane, but if you are driving, you should be fine. Just be prepared to stop a lot for restroom breaks!
I have also heard from people I know that you should NOT drink the water there. Buy Bottled water. Again, this is something that I heard from friends. I had a friend go to Mexico a few years ago and got sick from drinking the water because they use different chemicals that we are not used to.
As far as vaccines or medications, I would consult your doctor. Ultimately, you would want to get all of your questions answered by your doctor.
Personally, If my doctor said that I would be safe to travel, then I would go! If he/she advised not to, then I wouldn't.

Hope this helped.